67883-07-2

Usage

Derivative of ethanamine

A modified version of the simple chemical ethanamine, with additional functional groups attached to the nitrogen atom.

Common use as a herbicide

2-(3,5-dichlorophenoxy)ethanamine is widely utilized to control and prevent the growth of unwanted plants, particularly broadleaf weeds in agricultural and horticultural crops.

Plant growth regulator

The compound affects the growth processes of plants, interfering with their normal development and ultimately leading to their death.

Synthesis of other chemicals and pharmaceuticals

2-(3,5-dichlorophenoxy)ethanamine can be used as a starting material or intermediate in the production of various other chemicals and drugs.

Potential health and environmental hazards

Due to its toxic nature, it is crucial to handle and use 2-(3,5-dichlorophenoxy)ethanamine with caution to minimize risks to human health and the environment.

InChI:InChI=1/C8H9Cl2NO/c9-6-3-7(10)5-8(4-6)12-2-1-11/h3-5H,1-2,11H2

Upstream product

• 18800-31-2 1-(2-bromo-ethoxy)-3,5-dichloro-benzene 
• 591-35-5 3,5-dichlorophenol 

Relevant academic research and scientific papers

Design, synthesis, crystal structure, and herbicidal activity of novel pyrrolidine-2,4-dione derivatives incorporating an alkyl ether pharmacophore with natural tetramic acids as lead compounds

In order to discover green herbicides with novel molecular scaffolds, natural tetramic acids were used as lead compounds to design and synthesize four pyrrolidine-2,4-dione derivatives incorporating a chainlike alkoxyalkyl moiety (4a-4d) and nineteen pyrrolidine-2,4-dione derivatives incorporating a substituted phenoxyethyl moiety (10a-10s)viasubstitution, acylation, cyclization, and acidification reactions. The synthesized target compounds were confirmed by FT-IR,1H NMR,13C NMR and HRMS spectral analyses. The single-crystal structure of compound10awas analyzed by X-ray diffraction, which revealed that the 1-hydroxyethylidene group links the third position of the pyrrolidine heterocycle through a double bond with theZ-configuration. The herbicidal activity was evaluated using barnyard grass (Echinochloa crus-galli) and rape (Brassica campestris) as model plants by a Petri dish culture method. Most target compounds were found to possess moderate to good inhibitory activities against the plant growth at 100 μg mL?1. Among them, the compounds10qand10nshowed the highest herbicidal activities against the roots of barnyard grass and rape seedlings with the corresponding inhibition rates of 65.6% and 84.0%, respectively. This result indicated that pyrrolidine-2,4-dione derivatives incorporating a substituted phenoxyethyl moiety are worthy of further structural optimization.

Method for treating glaucoma

Methods of using prostaglandin agonists for the reduction of intraocular pressure, and accordingly glaucoma.

Prevention of loss and restoration of bone mass by certain prostaglandin agonists

Prostaglandin agonists of formula (I), in which, for example, A is a sulphonyl or acyl group, B is N or CH, M contains a ring and K and Q are linking groups, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits useful for the treatment of bone disorders including osteoporosis. STR1

Method of treating cardiac disorders with N-(aryloxyalkyl)-N'-(aminoalkyl)ureas

N-(Aryloxyalkyl)-N'-(aminoalkyl)ureas and thioureas having the formula: STR1 wherein R1 and R2 are hydrogen, loweralkyl, cycloalkyl, phenyl or phenyllower alkyl, and R3 and R4 are hydrogen, loweralkyl, phenyl and phenylalkyl or R3 and R4 taken together with the adjacent nitrogen form a heterocyclic residue are disclosed in a method of suppressing cardiac arrhythmias.