678982-30-4

Basic information

• Product Name: 1H-Azepine-1-carboxylic acid, hexahydro-3-hydroxy-4-[[(2S)-4-methyl-1-oxo-2-[[(1S)-2,2,2-trifluoro-1-[ 4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]ethyl]amino]pentyl]amino]-, phenylmethyl ester
• CAS NO: 678982-30-4
• Molecular Formula: C35H42F3N3O6S
• Molecular Weight: 689.796
• Mol File: 678982-30-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Azepine-1-carboxylic acid, hexahydro-3-hydroxy-4-[[(2S)-4-methyl-1-oxo-2-[[(1S)-2,2,2-trifluoro-1-[ 4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]ethyl]amino]pentyl]amino]-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Azepine-1-carboxylic acid, hexahydro-3-hydroxy-4-[[(2S)-4-methyl-1-oxo-2-[[(1S)-2,2,2-trifluoro-1-[ 4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]ethyl]amino]pentyl]amino]-, phenylmethyl ester(678982-30-4)
• EPA Substance Registry System: 1H-Azepine-1-carboxylic acid, hexahydro-3-hydroxy-4-[[(2S)-4-methyl-1-oxo-2-[[(1S)-2,2,2-trifluoro-1-[ 4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]ethyl]amino]pentyl]amino]-, phenylmethyl ester(678982-30-4)

Safety Data

• Hazardous Substances Data: 678982-30-4(Hazardous Substances Data)

Upstream product

• 603142-83-2 (S)-4-methyl-2-(((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)ethyl)amino)pentanoic acid 
• 150989-61-0 4(R,S)-amino-3(R,S)-hydroxyazepane-1-carboxylic acid benzyl ester 

Relevant articles and documents

CATHEPSIN INHIBITORS

This invention relates to a novel class of compounds, represented by the formula (I) below, wherein the meanings of R1, R2, R3 and R4 are indicated therein, which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis, osteoarthritis and rheumatoid arthritis.