678995-27-2Relevant academic research and scientific papers
Synthesis of novel melanocortin 4 receptor agonists and antagonists containing a succinamide core
Xi, Ning,Hale, Clarence,Kelly, Michael G.,Norman, Mark H.,Stec, Markian,Xu, Shimin,Baumgartner, James W.,Fotsch, Christopher
, p. 377 - 381 (2007/10/03)
A novel series of piperazines appended to a succinamide backbone were synthesized and found to have a high affinity for the melanocortin-4 receptor (IC50s ranging from 0.1 to 200 nM). Both agonists and antagonists of MC4R were prepared by modi
