679002-53-0Relevant academic research and scientific papers
Oxidative Route to Indoles via Intramolecular Amino-Hydroxylation of o-Allenyl Anilines
Lauta, Nicholas R.,Williams, Ryan E.,Smith, David T.,Kumirov, Vlad K.,Njardarson, Jon T.
, p. 10713 - 10723 (2021/07/31)
A new intramolecular oxidative amino-hydroxylation of o-allenyl anilines is reported. Treatment of carbamate-protected anilines with lead(IV) carboxylates in dichloromethane at room temperature results in facile tandem C-N (allene cyclization) and C-O bon
Construction of Azacycles Based on Endo-Mode Cyclization of Allenes
Mukai, Chisato,Kobayashi, Minoru,Kubota, Shoko,Takahashi, Yukie,Kitagaki, Shinji
, p. 2128 - 2136 (2007/10/03)
A new procedure for constructing monocyclic five- and six-membered azacycles by the endo-mode ring-closing reaction of allenylazido derivatives under neutral conditions has been developed. The azabicyclo[m.n.0] compounds were prepared by applying this newly developed procedure. The seven-membered azacycle was prepared when the allene possessing an unsubstituted carboxyl amido functionality was submitted to the basic conditions. In addition, indole and quinoline skeletons were synthesized using this procedure.
