67902-40-3Relevant academic research and scientific papers
Synthesis and substitution reactions of N-protected 2-(phenylselenonylmethyl)pyrrolidines
Cooper, Matthew A.,David Ward
, p. 181 - 187 (2007/10/03)
Alkyl phenyl selenides derived from the benzeneselenenyl chloride induced cyclization of N-protected pent-4-enylamines can be converted in good yield into the corresponding 2-hydroxymethyl- or 2-alkoxymethyl-substituted pyrrolidines by oxidation to the corresponding selenone, followed by reaction with water (or hydroxide) or with the corresponding alcohol. Details of the reactions and possible mechanisms for the substitution are discussed.
Cyclofunctionalization of Olefinic Urethanes Using Benzeneselenenyl Chloride in the Presence of Silica Gel: A General Route to Nitrogen Heterocycles
Clive, D. L. J.,Farina, Vittorio,Singh, Alok,Wong, Chi Kwong,Kiel, William, A.,Menchen, Steven M.
, p. 2120 - 2126 (2007/10/02)
Ethyl urethanes derived from Δ4 or Δ5 olefinic amines undergo cyclofunctionalization to afford pyrrolidines and piperidines, respectively, when treated with benzeneselenenyl chloride.The reaction is an efficient one when carried out in the presence of silica gel, yields generally being above 80percent for the examples studied.
