67907-43-1Relevant academic research and scientific papers
The acetalization of glyoxal by vicinal diols
Sangsari, Farid Hamedi,Chastrette, Francine,Chastrette, Maurice,Blanc, Alain,Mattioda, Georges
, p. 15 - 20 (2007/10/02)
The structure and stereochemistry of products obtained when vicinal diols are allowed to react with glyoxal were established with the aid of 13C NMR structure relationships.Hemiacetalization yields 1,4-dioxane-2,3-diols regardless of the diol reacted.The course of acetalization depends on the structure of the diol: trans-1,2-cyclohexanediol and analogs yield only 1,4,5,8-tetraoxadecalins as acetals, whereas cis-1,2-cyclohexanediol and 1,2-ethanediol yield mixtures containing mostly 2,2'-bi-1,3-dioxolanes.The isomeric distribution of products depends on the reaction conditions.
