6791-49-7

Basic information

• Product Name: (S)-2-amino-3-hydroxypropionamide
• Synonyms: (S)-2-amino-3-hydroxypropionamide;(S)-2-Amino-3-hydroxypropanamide;Serinamide
• CAS NO: 6791-49-7
• Molecular Formula: C₃H₈N₂O₂
• Molecular Weight: 104.10782
• EINECS: 229-862-8
• Mol File: 6791-49-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 444.7°C at 760 mmHg
• Flash Point: 222.8°C
• Appearance: /
• Density: 1.294g/cm³
• Vapor Pressure: 8.9E-10mmHg at 25°C
• Refractive Index: 1.522
• CAS DataBase Reference: (S)-2-amino-3-hydroxypropionamide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-amino-3-hydroxypropionamide(6791-49-7)
• EPA Substance Registry System: (S)-2-amino-3-hydroxypropionamide(6791-49-7)

Safety Data

• Hazardous Substances Data: 6791-49-7(Hazardous Substances Data)

Usage

General Description

(S)-2-amino-3-hydroxypropionamide, also known as (S)-serine, is a naturally occurring compound and a non-essential amino acid. It plays a crucial role in the biosynthesis of proteins and is also involved in the metabolism of purines and pyrimidines. This chemical is a key component of many important biological processes, including the synthesis of phospholipids, nucleotides, and the neurotransmitter glycine. It is also involved in the formation of the antioxidant glutathione and is important for the maintenance of muscle and immune function. (S)-2-amino-3-hydroxypropionamide is typically obtained through the diet, as it is found in various food sources such as meat, dairy, and soy products, and it can also be synthesized in the body from other amino acids.

InChI:InChI=1/C3H8N2O2/c4-2(1-6)3(5)7/h2,6H,1,4H2,(H2,5,7)

Upstream product

• 3262-72-4 (S)-N-(tert-butoxycarbonyl)serine 
• 5680-80-8 methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride 
• 2788-84-3 (S)-serine methyl ester 
• 70897-15-3 N-α-carbobenzoxy-L-serinamide 

Downstream Products

• 56-45-1 L-serin 
• 129678-29-1 Bz-Tyr-Ser-NH₂ 

Relevant articles and documents

HEMIAMINAL-TAG FOR PROTEIN LABELING AND PURIFICATION

The invention pertains to the synthesis, isolation, and characterization of hemiaminal for selective labeling of peptides, proteins, antibodies, and organic fragments with -C(=0) CH2NH2 and derivatives with -CH2NH2 group over -C(=0) CHRNH2 group (where R≠H). The invention also pertains to the method of single-site immobilization of proteins through N-terminus Gly on solid phase. The invention includes late-stage tagging of N-terminus Gly with an affinity tag, 19F NMR probe, and a fluorophore and a method for metal-free protein purification and isolation of analytically pure proteins.

Derivative of hyaluronic acid modified with amino-carboxylic acid

The present invention provides a hyaluronic acid derivative comprising disaccharide units of Formula (I), and a hyaluronic acid derivative/drug conjugate wherein one or more drugs are conjugated to the hyaluronic acid derivative.

Basic proline-amide derivatives of GE 2270 and GE 2270-like antibiotics

PCT No. PCT/EP96/00407 Sec. 371 Date Jul. 31, 1997 Sec. 102(e) Date Jul. 31, 1997 PCT Filed Feb. 1, 1996 PCT Pub. No. WO96/24607 PCT Pub. Date Aug. 15, 1996The present invention refers to basic amides derivatives of GE 2270 and GE 2270-like antibiotics of general formula (1), wherein the group GE represents the antibiotic core molecule. The amide derivatives of antibiotic GE 2270 of formula (I) are antimicrobial agents mainly active against gram positive bacteria.