6791-49-7

Basic information

• Product Name: (S)-2-amino-3-hydroxypropionamide
• Synonyms: (S)-2-amino-3-hydroxypropionamide;(S)-2-Amino-3-hydroxypropanamide;Serinamide
• CAS NO: 6791-49-7
• Molecular Formula: C₃H₈N₂O₂
• Molecular Weight: 104.10782
• EINECS: 229-862-8
• Mol File: 6791-49-7.mol

Chemical Properties

• Boiling Point: 444.7°C at 760 mmHg
• Flash Point: 222.8°C
• Appearance: /
• Density: 1.294g/cm³
• Vapor Pressure: 8.9E-10mmHg at 25°C
• Refractive Index: 1.522
• CAS DataBase Reference: (S)-2-amino-3-hydroxypropionamide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-amino-3-hydroxypropionamide(6791-49-7)
• EPA Substance Registry System: (S)-2-amino-3-hydroxypropionamide(6791-49-7)

Safety Data

• Hazardous Substances Data: 6791-49-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(S)-2-amino-3-hydroxypropionamide is used as a building block for the synthesis of various pharmaceutical compounds due to its involvement in protein biosynthesis and other essential biological processes.
Used in Nutraceutical Industry:
(S)-2-amino-3-hydroxypropionamide is used as a dietary supplement to support muscle and immune function, as it is a key component in the maintenance of these systems.
Used in Cosmetic Industry:
(S)-2-amino-3-hydroxypropionamide is used as an ingredient in cosmetic products for its antioxidant properties, which can help protect the skin from oxidative stress and promote skin health.
Used in Food Industry:
(S)-2-amino-3-hydroxypropionamide is used as a natural flavor enhancer and a nutritional supplement in various food products, as it is found in meat, dairy, and soy products and can be synthesized in the body from other amino acids.
Used in Research Applications:
(S)-2-amino-3-hydroxypropionamide is used as a research tool in the study of various biological processes, including protein synthesis, neurotransmission, and antioxidant mechanisms, due to its involvement in these pathways.

InChI:InChI=1/C3H8N2O2/c4-2(1-6)3(5)7/h2,6H,1,4H2,(H2,5,7)

Upstream product

• 2788-84-3 (S)-serine methyl ester 
• 5680-80-8 methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride 
• 3262-72-4 (S)-N-(tert-butoxycarbonyl)serine 
• 70897-15-3 N-α-carbobenzoxy-L-serinamide 

Downstream Products

• 56-45-1 L-serin 
• 129678-29-1 Bz-Tyr-Ser-NH₂ 

Relevant articles and documents

HEMIAMINAL-TAG FOR PROTEIN LABELING AND PURIFICATION

The invention pertains to the synthesis, isolation, and characterization of hemiaminal for selective labeling of peptides, proteins, antibodies, and organic fragments with -C(=0) CH2NH2 and derivatives with -CH2NH2 group over -C(=0) CHRNH2 group (where R≠H). The invention also pertains to the method of single-site immobilization of proteins through N-terminus Gly on solid phase. The invention includes late-stage tagging of N-terminus Gly with an affinity tag, 19F NMR probe, and a fluorophore and a method for metal-free protein purification and isolation of analytically pure proteins.

Synthetic method for chiral alpha-aminoamide compounds

The invention provides a synthetic method for chiral alpha-aminoamide compounds, belongs to the technical field of organic synthetic methodology, and concretely relates to a synthetic method for chiral alpha-aminoamide compounds, wherein the method has a simple process, low costs and good economy. The method comprises the following steps: 1, performing ammonolysis: adding substituted chiral alpha-aminocarboxylate hydrochloride into concentrated ammonia water, performing stirring for 4-12h under a room temperature, wherein each 1mmol substituted chiral alpha-aminocarboxylate hydrochloride is corresponding to 2-8mL the concentrated ammonia water; 2, after a reaction is finished, performing distillation for removing ammonia water after the reaction to obtain crude products chiral alpha-aminoamide compounds; and 3, performing filtration on the obtained crude products chiral alpha-aminoamide compounds by adopting a manner of adding a solvent or performing purification on the obtained crude products chiral alpha-aminoamide compounds through a manner of column chromatography which uses ammonia water as a mobile phase to obtain the products chiral alpha-aminoamide compounds. Compared with the prior art, a large number of an ammonia gas for ammonolysis is not needed in the method, the process and post-treatment are simple, costs are low and reaction time is short.

Derivative of hyaluronic acid modified with amino-carboxylic acid

The present invention provides a hyaluronic acid derivative comprising disaccharide units of Formula (I), and a hyaluronic acid derivative/drug conjugate wherein one or more drugs are conjugated to the hyaluronic acid derivative.

BIARYL HETEROCYCLIC AMINES, AMIDES, AND SULFUR-CONTAINING COMPOUNDS AND METHODS OF MAKING AND USING THE SAME

The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of biaryl heterocyclic amines, amides, and sulfur-containing compounds that are useful as such agents agents.

Basic proline-amide derivatives of GE 2270 and GE 2270-like antibiotics

PCT No. PCT/EP96/00407 Sec. 371 Date Jul. 31, 1997 Sec. 102(e) Date Jul. 31, 1997 PCT Filed Feb. 1, 1996 PCT Pub. No. WO96/24607 PCT Pub. Date Aug. 15, 1996The present invention refers to basic amides derivatives of GE 2270 and GE 2270-like antibiotics of general formula (1), wherein the group GE represents the antibiotic core molecule. The amide derivatives of antibiotic GE 2270 of formula (I) are antimicrobial agents mainly active against gram positive bacteria.