67916-54-5

Usage

Uses

Used in Pharmaceutical Industry:
Bis(4-methoxyphenyl)(pyridin-2-yl)methanol is used as an intermediate in the synthesis of pharmaceuticals for its anti-inflammatory and anti-cancer properties. It aids in the development of new drugs that can potentially treat various diseases and conditions.
Used in Organic Compounds Synthesis:
Bis(4-methoxyphenyl)(pyridin-2-yl)methanol is used as an intermediate in the synthesis of other organic compounds, contributing to the creation of a wide range of chemical products.
Used in Optoelectronic Industry:
Bis(4-methoxyphenyl)(pyridin-2-yl)methanol is used in the development of organic light-emitting diodes (OLEDs) and other optoelectronic applications due to its unique molecular structure and properties, which can enhance the performance of these devices.

Upstream product

• 2524-52-9 ethyl-2-picolinate 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 17624-36-1 2-pyridyllithium 
• 90-96-0 bis(p-methoxyphenyl)methanone 

Downstream Products

• 102237-74-1 4-(bis(4-methoxyphenyl)methyl)pyridine 
• 67916-64-7 7-methoxy-10-(4-methoxyphenyl)pyrido[1,2-a]indole 
• 603-41-8 4,4'-(2-pyridylmethylene)diphenol 

Relevant academic research and scientific papers

A process for preparing sodium new method (by machine translation)

The invention relates to a method for preparing (V) indicated by the sodium of the method, the method comprises the following steps: (a) in formula (I) indicated by the 2 - picolinic ester as the starting material, as shown in formula (II) of 4 - halogenated phenyl ether in the formula (III) Grignard reaction indicated by the 4', 4" - dialkoxy diphenyl - (2 - pyridine) - methanol (compound III). (B) 4 ', 4 "- dialkoxy diphenyl - (2 - pyridine) - methanol (compound III) in the Lewis acid under the action of removing a water molecule and alkoxy alkyl, formula (IV) as shown by a 4', 4" - dihydroxy phenyl - (2 - pyridine) - methane (compound IV). (C) 4', 4" - dihydroxy phenyl - (2 - pyridine) - methane with chlorosulfuric acid in sulfuric acid esterification reaction, sodium hydroxide after treatment, to obtain crude sodium, by recrystallization to obtain high-purity sodium (compound V). The present invention provides a kind of existing technology with the different sodium new preparation method, the method is simple in operation, the atom economy is high, is suitable for industrial production. (by machine translation)

An efficient synthesis of pyrido[1,2-a]indoles through aza-Nazarov type cyclization

Transition metal free Br?nsted acid mediated synthesis of biologically important pyrido[1,2-a]indole scaffolds through aza-Nazarov type cyclization of readily available diaryl(2-pyridyl)methanol using formic acid has been developed. This methodology has b

Iron-catalyzed C-H bond functionalization for the exclusive synthesis of pyrido[1,2-a]indoles or triarylmethanols

The efficient and selective iron-catalyzed C-H activation of 2-benzhydrylpyridine derivatives was employed for the preparation of pyrido[1,2-a]indoles through an intramolecular C-H amination reaction. In the presence of molecular oxygen as the sole oxidant, the same 2-benzhydrylpyridines were also used for the synthesis of the corresponding tertiary alcohols. In these approaches, the iron catalyst was used to selectively activate the C(sp2)-H bond of 2-benzhydrylpyridine, in the case of the intramolecular ring-closing C-H amination reaction in which the pyridine nitrogen atom was a directing group as well as a nucleophile, and the C(sp3)-H bond of the same compound, in the case of the oxidation reaction to give the corresponding triaryl carbinol.