67931-03-7

Upstream product

• 28664-18-8 2-(4-methylcyclohex-3-en-1-yl)propan-2-yl 2,2,2-trifluoroacetate 
• 5989-27-5 D-limonene 

Downstream Products

• 588716-01-2 (2S,5R,7R)-2,8,8-trimethyl-1-azatricyclo[3.2.1.0^2,7]octane 
• 588716-03-4 (1S,4R,6S)-1,3,3-trimethyl-2-azabicyclo[2.2.2]octan-6-yl acetate 
• 774214-66-3 (1R,4R,5R)-6-benzyl-4,7,7-trimethyl-6-azabicyclo[3.2.1]oct-4-yl acetate 
• 144370-96-7 (R)-N-{1-methyl-1-[4-methylcyclohex-3-en-1-yl]ethyl}acetamide 
• 774214-70-9 (R)-tert-butyl 1-methyl-1-[4-methylcyclohex-3-en-1-yl]ethylcarbamate 

Relevant academic research and scientific papers

Solvomercuration-Demercuration of Limonene with Hg(BF4)2; A Chemo- and Regiospecific Route to 8-Substituted p-Menthenes

Solvomercuration-demercuration of limonene with equimolar Hg(BF4)2 and excess nucleophile (-20 deg C) functionalizes the acyclic double bond and provides specifically 8-substituted p-menthenes.Key words: limonene; mercuration-demercuration; α-terpineol; mercuric tetrafluoroborate; p-menthenes

Synthesis of Aristoquinoline Enantiomers and Their Evaluation at the α3β4 Nicotinic Acetylcholine Receptor

The first synthesis of aristoquinoline (1), a naturally occurring nicotinic acetylcholine receptor (nAChR) antagonist, was accomplished using two different approaches. Comparison of the synthetic material's spectroscopic data to that of the isolated alkaloid identified a previously misassigned stereogenic center. An evaluation of each enantiomer's activity at the α3β4 nAChR revealed that (+)-1 is significantly more potent than (-)-1. This unexpected finding suggests that naturally occurring 1 possesses the opposite absolute configuration from indole-containing Aristotelia alkaloids.

Azacineole (1,3,3-trimethyl-2-azabicyclo[2.2.2]octane)

The synthesis and chemistry of azacineole were investigated. The paper stresses on the synthesis of compound and then seek its presence in various eucalypt trees. In regard with this, the two-step synthesis of azacineole obtained from limonene was present