67932-69-8

Basic information

• Product Name: 1H-Indole,2,3-dihydro-3-(1-methylethyl)-(9CI)
• Synonyms: 1H-Indole,2,3-dihydro-3-(1-methylethyl)-(9CI);3-Isopropylindoline
• CAS NO: 67932-69-8
• Molecular Formula: C₁₁H₁₅N
• Molecular Weight: 161.2435
• Product Categories: ISOPROPYL
• Mol File: 67932-69-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Indole,2,3-dihydro-3-(1-methylethyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole,2,3-dihydro-3-(1-methylethyl)-(9CI)(67932-69-8)
• EPA Substance Registry System: 1H-Indole,2,3-dihydro-3-(1-methylethyl)-(9CI)(67932-69-8)

Safety Data

• Hazardous Substances Data: 67932-69-8(Hazardous Substances Data)

Usage

Derived from

Indole (a heterocyclic aromatic organic compound)

Also known as

Tryptoline

Occurrence

Found in nature as a component of certain plant alkaloids

Pharmacological properties

Effects on the central nervous system, potential as an antimicrobial agent

Uses

Precursor in the synthesis of various pharmaceuticals and other organic compounds

Upstream product

• 16886-00-3 3-isopropyl indole 
• 108665-93-6 3-isopropyl-1,3-dihydroindol-2-one 
• 5085-04-1 3-Isopropylidene-1,3-dihydro-indol-2-one 
• 59-48-3 2-oxoindole 
• 18804-59-6 isovaleraldehyde phenylhydrazone 

Downstream Products

• 1314970-32-5 1-benzyl-3-isopropylindoline 
• 930790-66-2 (2S,3S)-3-(3-fluorophenyl)-3-(3-isopropyl-2,3-dihydro-1H-indol-1-yl)propane-1,2-diol 

Relevant articles and documents

CH activation and CH2 double activation of indolines by radical translocation: Understanding the chemistry of the indolinyl radical

CH activation and CH2 double activation of indolines at C2 may be achieved efficiently through radical translocation. The fate of the C2 indolinyl radical is dictated by the substitution at C3. Fragmentation, cyclisation and tandem cyclisation reactions leading to indole, azaheterocycle and azapropellane formation, respectively, are reported. The Royal Society of Chemistry 2011.

Phenylaminopropanol derivatives and methods of their use

The present invention is directed to phenylaminopropanol derivatives of formulae I, II, and III: [image] or a pharmaceutically acceptable salt thereof, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromyalgia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, schizophrenia, and combinations thereof.