679433-91-1 Usage
Uses
Used in Synthetic Chemistry:
5-Bromo-8-methoxyisoquinoline is used as a chemical intermediate for the synthesis of various compounds. Its unique structure and reactivity make it a valuable component in the preparation of complex organic molecules.
Used in Pharmaceutical Industry:
5-Bromo-8-methoxyisoquinoline is used as a building block in the development of new pharmaceutical compounds. Its potential applications in drug discovery and design are being explored due to its unique chemical properties and reactivity.
Used in Research and Development:
5-Bromo-8-methoxyisoquinoline is used as a research compound in academic and industrial laboratories. Its properties and reactivity are studied to gain insights into the synthesis of new materials and compounds, as well as to understand its potential applications in various fields.
Used in Material Science:
5-Bromo-8-methoxyisoquinoline is used as a component in the development of new materials with specific properties. Its incorporation into materials can lead to the creation of novel compounds with unique characteristics, such as improved stability or enhanced reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 679433-91-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,9,4,3 and 3 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 679433-91:
(8*6)+(7*7)+(6*9)+(5*4)+(4*3)+(3*3)+(2*9)+(1*1)=211
211 % 10 = 1
So 679433-91-1 is a valid CAS Registry Number.
679433-91-1Relevant academic research and scientific papers
Sit, Sing-Yuen,Xie, Kai,Jacutin-Porte, Swanee,Boy, Kenneth M.,Seanz, James,Taber, Matthew T.,Gulwadi, Amit G.,Korpinen, Carolyn D.,Burris, Kevin D.,Molski, Thaddeus F.,Ryan, Elaine,Xu, Cen,Verdoorn, Todd,Johnson, Graham,Nichols, David E.,Mailman, Richard B.
, p. 715 - 734 (2004)
Dinapsoline is a full D1 dopamine receptor agonist that produces robust rotational activity in the unilateral 6-OHDA rat model. This compound is orally active, and shows a low tendency to cause tolerance in rat models. The active enantiomer was determined to have the S-(+) configuration, and the opposite enantiomer is essentially devoid of biological activity. Taken together, dinapsoline has significant metabolic and pharmacological advantages over previous D1 agonists. In an attempt to define the structure-activity relationships (SARs) and to map out the key elements surrounding the unique structure of dinapsoline, core analogues and substitution analogues of the parent tetracyclic condensed ring structure were prepared. Based on a recently developed synthesis of dinapsoline and its enantiomers, both core and substitution analogues on all four rings (A, B′, C and D ring) of dinapsoline were synthesized. It was found that affinity for both D1and D2 receptors was decreased by most substituents on the A, B′, and C rings, whereas D ring substitutions preserved much of the dopamine receptor binding activity.
