679437-29-7

Upstream product

• 622-33-3 N-benzyloxyamine 
• 679437-26-4 (2S,3R)-3-((S)-2,2-Dimethyl-1-methylcarbamoyl-propylcarbamoyl)-2-hydroxy-6-phenyl-2-trifluoromethyl-hexanoic acid 
• 89226-12-0 (S)-2-amino-N,3,3-trimethylbutanamide 
• 679437-17-3 (2S,3R)-3-((S)-4-Benzyl-2-thioxo-oxazolidine-3-carbonyl)-2-hydroxy-6-phenyl-2-trifluoromethyl-hexanoic acid ethyl ester 
• 679437-23-1 (2S,3R)-3-((S)-2,2-Dimethyl-1-methylcarbamoyl-propylcarbamoyl)-2-hydroxy-6-phenyl-2-trifluoromethyl-hexanoic acid ethyl ester 
• 679437-21-9 (2S,3R)-2-Hydroxy-3-(3-phenyl-propyl)-2-trifluoromethyl-succinic acid 1-ethyl ester 

Relevant academic research and scientific papers

Stereochemically pure α-trifluoromethyl-malic hydroxamates: synthesis and evaluation as inhibitors of matrix metalloproteinases

The synthesis of trifluoromethyl (Tfm) analogs of known nanomolar matrix metalloproteinases (MMPs) inhibitors has been performed. The synthetic protocol is based on a moderately stereoselective aldol reaction of trifluoropyruvate with an N-acyl-oxazolidin

Synthesis and evaluation of stereopure α-trifluoromethyl-malic hydroxamates as inhibitors of matrix metalloproteinases

The total synthesis of trifluoromethyl (Tfm) analogs of known nanomolar matrix metalloproteinases (MMPs) inhibitors has been performed. The synthetic protocol is based on a moderately stereoselective aldol reaction of trifluoropyruvate with an N-acyl-oxaz