67969-62-4

Upstream product

• 113184-02-4 2,2-dimethyl-1-phenyl-decan-1-one semicarbazone 
• 6333-05-7 2-cyano-3,3-dimethyl-4-phenyl-butyric acid ethyl ester 
• 1589-82-8 phenylmagnesium bromide 
• 502760-08-9 2-methyl-2-bromodecane 
• 3396-02-9 2-methyldecan-2-ol 
• 6921-34-2 benzylmagnesium chloride 
• 101873-53-4 2,2-Dimethyl-1-phenyl-decanon-⁽⁴⁾ 
• 13705-45-8 3,3-dimethyl-4-phenylbutanenitrile 

Downstream Products

• 109560-01-2 2,2-Dimethyl-1-cyclohexyl-decan 

Relevant academic research and scientific papers

Silver-catalyzed benzylation and allylation of tertiary alkyl bromides with organozinc reagents

Silver salts catalyze the benzylation and allylation of tertiary alkyl bromides with organozinc reagents. The reactions create quaternary carbon centers efficiently. Treatment of gem-dibromoalkanes with benzylic or allylic zinc reagents under silver catalysis leads to dibenzylation or diallylation. The functional-group compatibility of the present reactions is wider than that of the previous reactions with Grignard reagents.

Silver-catalyzed benzylation and allylation reactions of tertiary and secondary alkyl halides with grignard reagents

Treatment of alkyl halides, including tertiary alkyl bromides, with benzylic or allylic Grignard reagent in the presence of a catalytic amount of silver nitrate in ether yielded the corresponding cross-coupling products in high yields. The coupling reactions of tertiary alkyl halides provide efficient access to quaternary carbon centers.