67977-85-9

Upstream product

• 67977-61-1 epi-Secopenicillin 
• 69780-18-3 6-epipenicillin sulfoxide 
• 74242-86-7 Diphenylmethyl-2-(3R,4R-3-benzamido-4-chlor-2-oxo-azetidin-1-yl)-3-chlormethyl-3-butenoat 
• 67977-79-1 (R)-3-chloromethyl-2-((1R)-7-oxo-3-phenyl-(1rH,5cH)-4-oxa-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-but-3-enoic acid benzhydryl ester 
• 108-98-5 thiophenol 

Downstream Products

• 67977-88-2 (R)-3-Hydroxymethyl-2-((1R,5S)-7-oxo-3-phenyl-4-oxa-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-but-3-enoic acid benzhydryl ester 
• 1186615-53-1 (2S,6R,7R)-7-Benzoylamino-3-chloro-3-chloromethyl-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester 
• 68314-04-5 (6R,7R)-7-Benzoylamino-3-chloromethyl-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 67977-91-7 (2R,6R,7R)-7-Benzoylamino-3-methylene-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester 

Relevant academic research and scientific papers

STEREOCONTROLLED, STRAIGHTFORWARD SYNTHESIS OF 3-SUBSTITUTED METHYL 7α-METHOXY-1-OXACEPHEMS

Stereocontrolled and industrially feasible synthesis of a new antibiotic 1a and related derivates, which is characterized by using all the carbon atoms of the penicillin skeleton, is described.