67977-95-1Relevant academic research and scientific papers
Preparation method of methylthiazoline
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Paragraph 0036; 0061; 0063-0067, (2020/11/12)
The invention provides a preparation method of methylthiazoline. According to the method, a one-pot-process low-temperature acylation esterification oxidation technology, an organic base catalysis chiral conversion technology, a desulfurization ring-opening synthesis technology, a comprehensive cyclic solvent utilization technology and a byproduct recycling technology are integrated, and the method is mature in technology, simple in synthesis process, few in reaction steps and low in raw material consumption and has the characteristics of good atom economy, good product quality and low cost.
Design, synthesis and antibacterial activity of novel 1-oxacephem analogs
He, Yi,Wu, Jian Bo,Lei, Fan,Chen, Pei,Hai, Li,Wu, Yong
scheme or table, p. 407 - 410 (2012/05/20)
A series of 1-oxacephem analogs were synthesized and their antibacterial properties against five strains of Gram-positive and Gram-negative bacteria were evaluated in vitro while ceftazidine was selected as control. Some of the tested compounds, compound 12c in particular, showed more active against three selected strains than the standard.
2,4,6-TRIPYRIDINIO-1,3,5-TRIAZINE TRICHLORIDE, A NEW AND MILD ESTERIFICATION AGENT FOR PREPARATION OF PENICILLIN ESTERS
Murakami, Masayuki,Hajima, Makoto,Takami, Fumitaka,Yoshioka, Mitsuru
, p. 2055 - 2064 (2007/10/02)
Cyanuric chloride reacted with 3-molar equivalents of pyridine to give 2,4,6-tripyridinio-1,3,5-triazine trichloride, which was found to condense penicilins with alcohols under mild conditions to afford penicillin esters in good yields.Application to prep
