679806-84-9

Usage

Uses

Used in Pharmaceutical Industry:
4-Pyrimidin-2-ylbenzoyl chloride is used as a key intermediate in the synthesis of pharmaceuticals for its ability to introduce the benzoyl group into various compounds, contributing to the development of new drugs.
Used in Agrochemical Industry:
4-Pyrimidin-2-ylbenzoyl chloride is used as a key intermediate in the synthesis of agrochemicals, playing a role in the creation of new pesticides or other agricultural products.
Used in Organic Synthesis:
4-Pyrimidin-2-ylbenzoyl chloride is used as a reagent in organic synthesis to introduce the benzoyl group into various compounds, facilitating the formation of new chemical entities for research and commercial applications.

InChI:InChI=1/C11H7ClN2O/c12-10(15)8-2-4-9(5-3-8)11-13-6-1-7-14-11/h1-7H

Upstream product

• 199678-12-1 4-(pyrimidine-2-yl)benzoic acid 

Downstream Products

• 917374-83-5 N-(Pyridin-3-ylmethyl)-10-(4-pyrimidin-2-ylbenzoyl)-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-3-carboxamide 

Relevant academic research and scientific papers

C-H and N-H Bond Annulation of Benzamides with Isonitriles Catalyzed by Cobalt(III)

A simple efficient, atom-economical procedure was developed for the cobalt-catalyzed C-H bond annulation of benzamides with isonitriles under mild conditions. The reaction tolerates a variety of functional group including heterocycles. Diverse 3-(alkylimino)-2-quinolin-8-yl-2,3-dihydro-1 H -isoindol-1-ones were synthesized using isonitriles as the C1 source through C-H and N-H bond annulation via C-H bond activation in a 'green' solvent. Vinylamides were also used similarly with tert -butyl isonitrile to give 3-(tert -butylimino)-1-quinolin-8-yl-1 H -pyrrol-2(5 H)-ones.

Pyrrolobenzodiazepine pyridine carboxamides and derivatives as follicle-stimulating hormone receptor antagonists

This invention provides pyrrolobenzodiazepine pyridine carboxamides selected from those of Formula (1), which act as follicle stimulating hormone receptor antagonists. The invention also provides pharmaceutical compositions and methods of treatment utilizing the compounds of Formulae (1) and (2).