679808-75-4Relevant academic research and scientific papers
Asymmetric synthesis of β-amino acid and amide derivatives by catalytic conjugate addition of aromatic amines to N-alkenoylcarbamates
Li, Kelin,Cheng, Xiaohui,Hii, King Kuok
, p. 959 - 964 (2004)
We report a highly active palladium catalyst for the enantioselective conjugate addition of primary aromatic amines to N-alkenoylcarbamates, furnishing β-amino N-Boc-amides in extremely high yields (>99%) and unprecedented optical purity (>99% ee) with just 2 mol % catalyst loading. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.
Method of hydroaminating N-alkenoylcarbamates with primary aromatic amines
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Page/Page column 4, (2008/06/13)
The invention provides methods for hydroaminating N-alkenoyl carbamates with aromatic amines.
PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES
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Page/Page column 161-162, (2008/06/13)
Disclosed herein are compounds represented by Structural Formula: (I) and (I-A). Also disclosed is the use of such compounds for inhibiting the G-protein coupled receptor referred to as chemoattractant receptor-homologous molecule expressed on Th2, or simply "CRTH2" for the treatment of inflammatory disorders. The variables in Structural Formula (I) and (I-A) are defined herein.
