679812-27-2

Upstream product

• 862670-54-0 (R)-4-Benzyl-3-[(2R,3S)-3-(tert-butyl-dimethyl-silanyloxy)-7-(4-methoxy-benzyloxy)-2-methyl-heptanoyl]-oxazolidin-2-one 
• 862670-53-9 (R)-4-Benzyl-3-[(2R,3S)-3-hydroxy-7-(4-methoxy-benzyloxy)-2-methyl-heptanoyl]-oxazolidin-2-one 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 131375-69-4 5-((4-methoxybenzyl)oxy)pentanal 

Downstream Products

• 862670-61-9 (2R,3S)-3-(tert-Butyl-dimethyl-silanyloxy)-7-(4-methoxy-benzyloxy)-2-methyl-heptanoic acid (2R,3R,5S)-5-[(2R,3R,4R)-3-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-4-methyl-tetrahydro-pyran-2-yl]-2-vinyl-tetrahydro-furan-3-yl ester 

Relevant academic research and scientific papers

Synthesis of the common left-half part of pectenotoxins

The common left-half [C31-C33(OC1-C7)-C40] part of pectenotoxins has been synthesized convergently from the C31-C35, C36-C40, and C1-C7 parts. The C31-C35 part, prepared via a new route shorter than our previous route, was coupled with the C36-C40 part through reductive lithiation and addition reactions to give an adduct stereoselectively, which was converted to a cyclic acetal corresponding to the C31-C40 part. The left-half was synthesized by a three-step process including esterification of the C31-C40 part with the C1-C7 part.