67983-55-5Relevant academic research and scientific papers
Progesterone antagonists for the production of pharmaceutical agents for the treatment of dysfunctional uterine bleeding
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, (2008/06/13)
Competitive progesterone antagonists (antigestagens) are suitable for the production of pharmaceutical agents for the treatment of forms of dysfunctional uterine bleeding (metrorrhagias, menorrhagias, hypermenorrhea).
Method for treating endometriosis or leiomyomata uteri with a competitive progesterone antagonist and a gestagen
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, (2008/06/13)
PCT No. PCT/EP95/02998 Sec. 371 Date Jun. 10, 1997 Sec. 102(e) Date Jun. 10, 1997 PCT Filed Jul. 27, 1995 PCT Pub. No. WO96/03130 PCT Pub. Date Feb. 8, 1996This invention relates to the use of a product that contains in combination individual dosage units of a competitive progesterone antagonist and individual dosage units of a gestagen for its sequential, oral administration, in which each individual dosage unit that contains the competitive progesterone antagonist contains the latter in a non-abortion-inducing amount for the production of a pharmaceutical agent for treating endometriosis or leiomyomata uteri.
REGIO AND STEREOSPECIFIC SYNTHESIS OF 11β-SUBSTITUTED 19-NORSTEROIDS. Influence of 11β-substitution on progesterone receptor affinity.
Belanger, A.,Philibert, D.,Teutsch, G.
, p. 361 - 382 (2007/10/02)
The convenient synthesis of a series of 11β-substituted 17-ethynyl-17β-hydroxy-4,9-estradien-3-ones and their corresponding estradiols is reported.Relative affinities for the progestin and estrogen receptors showed very specific interactions between the p
