679834-46-9Relevant academic research and scientific papers
PYRROLOPYRIMIDINE NUCLEOSIDES AND ANALOGS THEREOF USEFUL AS ANTIVIRAL AGENTS
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Paragraph 00315-00318, (2017/03/08)
The present disclosure provides pyrrolopyrimidine nucleoside analogs of the Formula I, Formula IA, Formula IB, or Formula II and phospholipid conjugates and pharmaceutical compositions thereof wherein Rc and A are defined herein. Also presented are methods of treating and/or preventing viral infection and/or viral infection-associated disease or disorder with one or more compounds of Formula I, Formula IA, Formula IB, or Formula II.
Synthesis and Antiviral Activity of 2-Substituted Analogs of Triciribine
Porcari, Anthony R.,Ptak, Roger G.,Borysko, Katherine Z.,Breitenbach, Julie M.,Drach, John C.,Townsend, Leroy B.
, p. 2171 - 2193 (2007/10/03)
Triciribine (TCN) and triciribine monophosphate (TCN-P) have antiviral and antineoplastic activity at low or submicromolar concentrations. In an effort to improve and better understand this activity, we have conducted a structure-activity relationship stu
