679841-34-0

Upstream product

• 679841-33-9 (3R,5S,1'Z)-2-ethylidene-3-dimethyl(phenyl)silyl-5-methylcyclohexanone 
• 679841-38-4 (3R,5S,2'R)-2-(2'-butyl)-1-tert-butyl(dimethyl)silyloxy-3-dimethyl(phenyl)silyl-5-methylcyclohexene 

Downstream Products

• 679841-60-2 (2R,3R,5S)-2-((R)-sec-Butyl)-3-(dimethyl-phenyl-silanyl)-5-methyl-cyclohexanone oxime 

Relevant academic research and scientific papers

An approach to open-chain 1,5-stereocontrol using a silyl group

Nucleophilic attack by an ethylcuprate on the α,β-unsaturated ketone 3 takes place anti to the silyl group to give largely (96:4) a single product 4, fragmentation of which removes the silyl group, and reveals a pair of stereogenic centres having an open-chain 1,5 relationship 9.