680189-73-5

Upstream product

• 100-11-8 1-bromomethyl-4-nitro-benzene 

Downstream Products

• 336192-68-8 2-tert-butoxycarbonylamino-2-(4-nitro-benzyl)-4-oxo-butyric acid methyl ester 
• 336192-73-5 [4-(4-nitro-benzyl)-3-oxo-2,3,4,5-tetrahydro-pyridazin-4-yl]-carbamic acid tert-butyl ester 
• 336192-78-0 [4-(4-nitro-benzyl)-3-oxo-hexahydro-pyridazin-4-yl]-carbamic acid tert-butyl ester 
• 336192-87-1 7-tert-butoxycarbonylamino-7-(4-nitro-benzyl)-8-oxo-5,6,7,8-tetrahydro-3H-pyrazolo[1,2-a]pyridazine-1-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

The synthesis of β-strand mimetic templates via regioselective 1,3-dipolar cycloaddition with vinylsulfone

We have developed a practical synthetic route to constrained β-strand mimetic templates by regioselective 1,3-dipolar cycloaddition of azomethine imines with vinyl sulfone. A small library of β-strand mimetic templates was generated which include potent and selective inhibitors of serine proteases.