680203-53-6Relevant academic research and scientific papers
PYRAZOLE MAGL INHIBITORS
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Paragraph 00395; 00483, (2018/12/13)
Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of monoacylglycerol lipase (MAGL). Furthermore, the subject compounds and compositions are useful for the treatment of pain.
Towards a new generation of potential antipsychotic agents combining D 2 and 5-HT1A receptor activities
Cuisiat, Stephane,Bourdiol, Nathalie,Lacharme, Vincent,Newman-Tancredi, Adrian,Colpaert, Francis,Vacher, Bernard
, p. 865 - 876 (2007/10/03)
We report the discovery and the synthesis of novel, potential antipsychotic compounds combining potent dopamine D2 receptor antagonist and serotonin 5-HT1A receptor agonist properties in the same molecule. We describe the structure-a
3-(Cyclopenten-1-yl)-benzyl-or 3-(cyclopenten-1-yl)-heteroarylmethyl-amine derivatives and use thereof as medicines for treating schizophrenia
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Page/Page column 6-7, (2010/02/15)
The invention provides compounds of the formula: wherein (a) is a single or double bond; W is CH, CH2, CHCH3, CCH3, C(CH3)2, C(CH2)2 or C(CH2)3, provided th
