680227-80-9Relevant academic research and scientific papers
Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors
Qiao, Lei,Baumann, Christian A.,Crysler, Carl S.,Ninan, Nisha S.,Abad, Marta C.,Spurlino, John C.,Desjarlais, Renee L.,Kervinen, Jukka,Neeper, Mike P.,Bayoumy, Shariff S.,Williams, Robyn,Deckman, Ingrid C.,Dasgupta, Malini,Reed, Rolanda L.,Huebert, Norman D.,Tomczuk, Bruce E.,Moriarty, Kevin J.
, p. 123 - 128 (2007/10/03)
The discovery, SAR, and X-ray crystal structure of novel biarylaminoacyl-(S)-2-cyano-pyrrolidines and biarylaminoacylthiazolidines as potent inhibitors of dipeptidyl peptidase IV (DPP IV) are reported.
