680230-17-5

Upstream product

• 15761-38-3 L-N-Boc-Ala 

Downstream Products

• 680231-14-5 N-[4-oxo-2-phenyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-propionamide 
• 680229-37-2 N₂-[(2S)-2-hydroxy-4-methyl-1-oxo-pentyl]-N₁-[(2R,3S)-4-oxo-2-phenyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-L-alaninamide 
• 680230-18-6 N₁-[(2R,3S)-4-oxo-2-phenyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-L-alaninamide 
• 680232-26-2 N₁-[(2,3-cis)-4-oxo-2-phenyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl]-L-alaninamide 

Relevant academic research and scientific papers

NOVEL LACTAMS AND USES THEREOF

Compounds having the formula (I) pharmaceutical compositions containing them and their methods of use for the treatment of neurological disorders related to amyloid ? protein production and neurological disorders such as Alzheimer's disease.. These compounds inhibit γ secretase and thereby inhibit the production of amyloid ? protein, thereby acting to prevent the formation of neurological deposits of amyloid protein.