680230-90-4Relevant academic research and scientific papers
CHEMICAL COMPOUNDS
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Page/Page column 95, (2008/06/13)
The invention provides a new method for treating disorders associated with activation of the Notch signal transduction pathway comprising administering an effective amount of a compound of Formula (I), in free form or in a pharmaceutically acceptable salt
Synthesis of single-enantiomer 6-hydroxy-7-phenyl-1,4-oxazepan-5-ones
Becker, Christopher W.,Dembofsky, Bruce T.,Hall, James E.,Jacobs, Robert T.,Pivonka, Don E.,Ohnmacht, Cyrus J.
, p. 2549 - 2561 (2007/10/03)
An efficient two-step preparation of (6R,7R)-6-hydroxy-7-phenyl-1,4- oxazepan-5-ones (1) starting from aminoethanols and (2R,3S)-3-phenyloxirane-2- carboxylic ethyl ester or potassium salt has been described. The most efficient catalyst identified for the
