680232-40-0Relevant academic research and scientific papers
CHEMICAL COMPOUNDS
-
Page/Page column 180, (2008/06/13)
The invention provides a new method for treating disorders associated with activation of the Notch signal transduction pathway comprising administering an effective amount of a compound of Formula (I), in free form or in a pharmaceutically acceptable salt
NOVEL LACTAMS AND USES THEREOF
-
Page 157, (2010/02/06)
Compounds having the formula (I) pharmaceutical compositions containing them and their methods of use for the treatment of neurological disorders related to amyloid ? protein production and neurological disorders such as Alzheimer's disease.. These compounds inhibit γ secretase and thereby inhibit the production of amyloid ? protein, thereby acting to prevent the formation of neurological deposits of amyloid protein.
