68027-15-6

Basic information

• Product Name: Hederagenin 3-O-α-L-rhaMnopyranosyl(1→2)-(β-D-glucopyranosyl(1→4))-α-L-arabinopyranoside
• Synonyms: Hederagenin 3-O-α-L-rhaMnopyranosyl(1→2)-(β-D-glucopyranosyl(1→4))-α-L-arabinopyranoside;Pulsatilla Saponin D (90%);Pulsatilla saponin D (SB365)
• CAS NO: 68027-15-6
• Molecular Formula: C₄₇H₇₆O₁₇
• Molecular Weight: 913.09614
• EINECS: 211-708-6
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;reagent;standard substance
• Mol File: 68027-15-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 239-241℃
• Boiling Point: 997.6±65.0 °C(Predicted)
• Appearance: /
• Density: 1.40±0.1 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Methanol (Slightly), Pyridine
• PKA: 4.63±0.70(Predicted)
• CAS DataBase Reference: Hederagenin 3-O-α-L-rhaMnopyranosyl(1→2)-(β-D-glucopyranosyl(1→4))-α-L-arabinopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: Hederagenin 3-O-α-L-rhaMnopyranosyl(1→2)-(β-D-glucopyranosyl(1→4))-α-L-arabinopyranoside(68027-15-6)
• EPA Substance Registry System: Hederagenin 3-O-α-L-rhaMnopyranosyl(1→2)-(β-D-glucopyranosyl(1→4))-α-L-arabinopyranoside(68027-15-6)

Safety Data

• Hazardous Substances Data: 68027-15-6(Hazardous Substances Data)

Usage

Description

Pulsatilla saponin D is an oleanane-type saponin that has been found in P. koreana and has anticancer activity. It is cytotoxic to A549, SKOV3, SK-MEL-2, and HCT15 cells (EC50s = 11.25, 13.17, 3.04, and 11.86 μM, respectively). Pulsatilla saponin D (6 mg/kg per day) reduces tumor volume in a murine Lewis lung carcinoma model.

Uses

Pulsatilla Saponin D shows antiangiogenic and antitumor activity.

Relevant articles and documents

Triterpenoid saponins from Pulsatilla cernua Spreng. I.

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