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6-chloro-N2-(4-methoxy-phenyl)-N4-(4-nitro-phenyl)-[1,3,5]triazine-2,4-diamine is a complex organic compound with the molecular formula C15H11ClN6O3. It features a triazine ring system, which is a six-membered aromatic ring containing three nitrogen atoms. The compound has a chlorine atom at the 6-position, a 4-methoxy-phenyl group attached to the N2 position, and a 4-nitro-phenyl group at the N4 position. The 2,4-diamine functional groups are present at the 2 and 4 positions of the triazine ring. 6-chloro-N2-(4-methoxy-phenyl)-N4-(4-nitro-phenyl)-[1,3,5]triazine-2,4-diamine is known for its potential applications in the synthesis of various pharmaceuticals and agrochemicals due to its unique structure and reactivity.

6803-95-8

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6803-95-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6803-95-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,8,0 and 3 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6803-95:
(6*6)+(5*8)+(4*0)+(3*3)+(2*9)+(1*5)=108
108 % 10 = 8
So 6803-95-8 is a valid CAS Registry Number.

6803-95-8Downstream Products

6803-95-8Relevant academic research and scientific papers

Synthesis, docking, in vitro and in vivo antimalarial activity of hybrid 4-aminoquinoline-1,3,5-triazine derivatives against wild and mutant malaria parasites

Bhat, Hans Raj,Singh, Udaya Pratap,Gahtori, Prashant,Ghosh, Surajit Kumar,Gogoi, Kabita,Prakash, Anil,Singh, Ramendra K.

, p. 265 - 271 (2015/03/04)

A new series of hybrid 4-aminoquinoline-1,3,5-triazine derivatives was synthesized by a four-step reaction. Target compounds were screened for in vitro antimalarial activity against chloroquine-sensitive (3D-7) and chloroquine-resistant (RKL-2) strains of Plasmodium falciparum. Compounds exhibited, by and large, good antimalarial activity against the resistant strain, while two of them, that is 8g and 8a, displayed higher activity against both the strains of P. falciparum. Additionally, docking study was performed on both wild (1J3I.pdb) and quadruple mutant (N51I, C59R, S108 N, I164L, 3QG2.pdb) type pf-DHFR-TS to highlight the structural features of hybrid molecules. A series of hybrid 4-aminoquinoline was synthesized and evaluated for antimalarial activity against chloroquine-sensitive (3D-7) and chloroquine-resistant (RKL-2) strains of P. falciparum.

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