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Ω-Hydroxydiethylstilbestrol is a synthetic derivative of diethylstilbestrol (DES), a nonsteroidal estrogen that was widely used in the past for various medical purposes, including the prevention of miscarriages and treatment of menopausal symptoms. This chemical compound is characterized by the presence of a hydroxyl group (-OH) at the omega (Ω) position, which is the terminal carbon atom in the molecule. The addition of this hydroxyl group can alter the pharmacological properties of the parent compound, potentially affecting its potency, duration of action, and metabolic profile. While DES itself has been associated with certain health risks and is no longer in clinical use, research on its derivatives, such as Ω-hydroxydiethylstilbestrol, may provide insights into the structure-activity relationships of estrogenic compounds and contribute to the development of safer and more effective medications.

68034-38-8

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68034-38-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 68034-38-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,0,3 and 4 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 68034-38:
(7*6)+(6*8)+(5*0)+(4*3)+(3*4)+(2*3)+(1*8)=128
128 % 10 = 8
So 68034-38-8 is a valid CAS Registry Number.

68034-38-8Downstream Products

68034-38-8Relevant academic research and scientific papers

SYNTHESIS OF METABOLIC INTERMEDIATES OF DIETHYLSTILBESTROL

Hill, Kenneth A.,Peterson, Dorothy M.,Damodaran, Kalyani M.,Rao, P. Narasimha

, p. 327 - 344 (2007/10/02)

This report details the synthesis of 1) 3,4,4'-trihydroxy-α,α'-diethyl-trans-stilbene; 2) 3,4-bis-(p-hydroxyphenyl)-trans-3-hexenol; 3) 3,4-bis-(p-hydroxyphenyl)-2,4-cis,cis-hexadienol; 4) 3,4-bis-(3'-methoxy-4'-hydroxyphenyl)-trans-3-hexene; 5) 3,4-bis-(3',4'-dimethoxyphenyl)-trans-3-hexene.These compounds are suspected metabolites of diethylstilbestrol.

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