680573-16-4Relevant academic research and scientific papers
Rapid and efficient synthesis of α(1-2)mannobiosides
Reina, José J.,Di Maio, Antonio,Ramos-Soriano, Javier,Figueiredo, Rute C.,Rojo, Javier
, p. 2873 - 2882 (2016/03/12)
α(1,2)mannobiosides with different substituents at the reducing end have been synthesized by a common strategy using benzoyls as the permanent protecting groups and an acetyl as the orthogonal protecting group at position C2 of the glycosyl acceptor. The
Synthesis of mannopyranose disaccharides as photoaffinity probes for mannosyltransferases in Mycobacterium tuberculosis
Pathak, Ashish K.,Pathak, Vibha,Riordan, James M.,Gurcha, Sudagar S.,Besra, Gurdyal S.,Reynolds, Robert C.
, p. 683 - 691 (2007/10/03)
Mannosyltransferases play a crucial role in mycobacterial cell-wall biosynthesis and are potential new drug targets for the treatment of tuberculosis. Herein, we describe the synthesis of α-(1→2)- and α-(1→6)-linked mannopyranosyl disaccharides possessing
