680591-93-9Relevant academic research and scientific papers
Explorations on the total synthesis of the unusual marine alkaloid chartelline A
Sun, Cuixiang,Lin, Xichen,Weinreb, Steven M.
, p. 3159 - 3166 (2007/10/03)
In work directed toward a total synthesis of chartelline A (1a), a strategy was investigated to construct the 10-membered ring of this marine alkaloid via an intramolecular aldehyde/β-lactam cyclocondensation to form the macrocyclic enamide functionality.
Synthesis of model compound containing an indole spiro-β-lactam moiety with vinylchloride in chartellines
Nishikawa, Toshio,Kajii, Shigeo,Isobe, Minoru
, p. 440 - 441 (2007/10/03)
A model compound containing an indole β-lactam moiety bearing vinylchloride in chartellines was synthesized from the Mannich reaction of isatin imine with ketene silyl acetal, β-lactam formation of the resulting β-amino ester, and copper(I)-mediated coupl
