680594-15-4

Upstream product

• 29111-46-4 N-phenylaminoacetyl hydrazide 
• 103-72-0 phenyl isothiocyanate 

Downstream Products

• 680594-25-6 [4-phenyl-5-(N-phenylamino)methyl-1,2,4-triazol-3-yl]thioglycolylhydrazide 
• 680594-23-4 ethyl [4-phenyl-5-(N-phenylamino)methyl-1,2,4-triazol-3-yl]thioglycolate 
• 680594-19-8 5-mercapto-4-phenyl-3-(N-phenylamino)methyl-1,2,4-triazole 

Relevant academic research and scientific papers

Synthesis of some functionalized arylaminomethyl-1,2,4-triazoles, 1,3,4-oxa- and thiadiazoles

Thiosemicarbazides undergo different cyclization reactions to give five membered heterocycles. The product of cyclization depends on the reagent used. This cyclization leads to the formation of 1,3,4-oxadiazole, 1,3,4-thiadiazole and 1,2,4-triazole derivatives. The reaction of thioglycolyl hydrazide derivatives of the 1,2,4-triazole compounds was discussed. The activity against hepatitis B virus (HBV) has been tested.