680611-16-9Relevant academic research and scientific papers
Indazoles useful in treating cardiovascular diseases
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Page/Page column 28, (2008/06/13)
This invention provides compounds of Formula (I) or (Ia): that are useful in the treatment or inhibition of LXR mediated diseases.
SUBSTITUTED 4-(INDAZOL-3-YL)PHENOLS AS ESTROGEN RECEPTOR (ER) LIGANDS AND THEIR USE IN THE TREATMENT OF INFLAMMATORY DISEASES
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Page 48, (2008/06/13)
This invention provides compound of formulae I or II having the structure wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are as defined in the specification or a pharmaceutically acceptable salt thereof which are useful for the treatment of the infla
Synthesis and activity of substituted 4-(indazol-3-yl)phenols as pathway-selective estrogen receptor ligands useful in the treatment of rheumatoid arthritis
Steffan, Robert J.,Matelan, Edward,Ashwell, Mark A.,Moore, William J.,Solvibile, William R.,Trybulski, Eugene,Chadwick, Christopher C.,Chippari, Susan,Kenney, Thomas,Eckert, Amy,Borges-Marcucci, Lisa,Keith, James C.,Xu, Zhang,Mosyak, Lydia,Harnish, Douglas C.
, p. 6435 - 6438 (2007/10/03)
Pathway-selective ligands for the estrogen receptor (ER) inhibit NF-κB-mediated inflammatory gene expression causing a reduction of cytokines, chemokines, adhesion molecules, and inflammatory enzymes. SAR development of a series of 4-(indazol-3-yl)phenols
