680611-86-3

Usage

Uses

Used in Pharmaceutical Industry:
SGA 293 is used as an anti-inflammatory agent for its ability to modulate aryl hydrocarbon receptor activity. This modulation helps in reducing inflammation and can be beneficial in treating various inflammatory conditions.
Used in Medical Research:
In the field of medical research, SGA 293 is used as a selective modulator of Ah receptor activity. This property makes it a valuable tool for studying the role of Ah receptors in various biological processes and their potential as therapeutic targets for different diseases.
Used in Anti-Inflammatory Applications:
SGA 293 is employed as an anti-inflammatory agent, particularly in the treatment of conditions where inflammation plays a significant role, such as autoimmune disorders, chronic inflammatory diseases, and certain types of cancer. Its ability to modulate Ah receptor activity allows it to exert inhibitory effects on the inflammatory response, providing potential therapeutic benefits.

Upstream product

• 106-95-6 allyl bromide 
• 680611-18-1 3-(2,4-dimethoxyphenyl)-7-(trifluoromethyl)-1H-indazole 

Relevant academic research and scientific papers

Development of a selective modulator of aryl hydrocarbon (Ah) receptor activity that exhibits anti-inflammatory properties

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that mediates the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin. However, the role of the AHR in normal physiology is still an area of intense investigation. For example, thi

Preparation and purification of 4-(indazol-3-yl) phenols

The present invention concerns processes for the production and purification of compounds of the formula: where R1-R10 are as defined in the specification. Preferred processes of the invention utilize a lithium bis(trimethylsilyl)ami

Method of treating or preventing myocardial ischemia-reperfusion injury using NF-kB inhibitors

The present invention concerns a method of treatment or prevention of myocardial ischemia-reperfusion injury by diagnosing that a person is in need of treatment or prevention of myocardial ischemia-reperfusion injury and administering a therapeutically ef

Estrogen receptor structure

Estrogen receptor ligands, estrogen receptor polypeptide/ligand complexes, crystals of estrogen receptor polypeptide/ligand complexes, and related methods and software systems are disclosed.

Methods of treating inflammatory bowel disease using NF-kB inhibitors

The present invention concerns a method of treating inflammatory bowel disease by diagnosing that a person is in need of treatment for inflammatory bowel disease and administering a therapeutically effective amount of a ligand which modulates NF-kB transc

METHODS OF TREATING ATHEROSCLEROSIS USING NF-kB INHIBITORS

The present invention concerns a method of treating atherosclerosis by diagnosing that a person is in need of treatment for atherosclerosis and administering a therapeutically effective amount of a ligand which modulates NF-kB transcription factor by inte

Methods of treating rheumatoid arthritis using NF-kB inhibitors

The present invention concerns a method of treating rheumatoid arthritis by diagnosing that a person is in need of treatment for rheumatoid arthritis and administering a therapeutically effective amount of a ligand which modulates NF-kB transcription fact

Methods of treating atherosclerosis using NF-kB inhibitors

The present invention concerns a method of treating atherosclerosis by diagnosing that a person is in need of treatment for atherosclerosis and administering a therapeutically effective amount of a ligand which modulates NF-kB transcription factor by inte

METHOD OF TREATING RHEUMATOID ARTHRITIS USING NF-kB INHIBITORS

The present invention concerns a method of treating rheumatoid arthritis by diagnosing that a person is in need of treatment for rheumatoid arthritis and administering a therapeutically effective amount of a ligand which modulates NF-kB transcription fact

USE OF ESTROGEN RECEPTOR LIGANDS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE

The present invention concerns a method of treating inflammatory bowel disease by diagnosing that a person is in need of treatment for inflammatory bowel disease and administering a therapeutically effective amount of a ligand which modulates NF-kB transc