680624-13-9Relevant academic research and scientific papers
Novel chiral bisformamide-promoted asymmetric allylation of benzaldehyde with allyltrichlorosilane
Ishimaru, Kaori,Ono, Kaori,Tanimura, Yuya,Kojima, Takakazu
scheme or table, p. 3627 - 3634 (2011/10/09)
Novel chiral bisformamides have been prepared from (R,R)-1,2- cyclohexanediamine and utilized as Lewis bases in the asymmetric allylation of benzaldehyde with allyltrichlorosilane. The reaction in the presence of Lewis base 1i gave an 83:17 enantiomeric r
Chiral relay in NHC-mediated asymmetric β-lactam synthesis I; substituent effects in NHCs derived from (1R,2R)-cyclohexane-1,2-diamine
Duguet, Nicolas,Donaldson, Adele,Leckie, Stuart M.,Douglas, James,Shapland, Peter,Brown, Thomas B.,Churchill, Gwydion,Slawin, Alexandra M.Z.,Smith, Andrew D.
experimental part, p. 582 - 600 (2010/08/19)
The synthesis of a range of C2-symmetric imidazolinium salts from (1R,2R)-cyclohexane-1,2-diamine, and an evaluation of the reactivity and asymmetric induction of the derived NHCs as catalysts for the asymmetric synthesis of β-lactams, is reported. In this series, optimal enantioselectivity (up to 70% ee) is observed using N-benzyl or N-1-naphthylmethyl-substituted NHCs, consistent with a chiral relay effect operating to dictate the stereochemical outcome of this reaction.
Copper(I) catalysis: Synthesis of N,N′-diarylated and N-aryl,N′-formylated chiral C2-symmetric diamines
Alakonda, Laxhmaiah,Periasamy, Mariappan
experimental part, p. 3859 - 3863 (2010/03/03)
Chiral N,N′-diaryl C2-symmetric diamines and N-aryl,N′-formyl-trans-(1R,2R)-diaminocyclohexane are readily accessed by copper catalyzed N,N′-diarylation and N-aryl,N′-formylation of trans-(1R,2R)-diaminocyclohexane with aryl bromides. N,N′-diar
Scandium triflate catalyzed aminolysis of meso-aziridines
Peruncheralathan, Saravanan,Henze, Michael,Schneider, Christoph
, p. 2289 - 2291 (2008/02/09)
The aminolysis of meso-N-phenyl aziridines is efficiently catalyzed with just 1 mol% of Sc(OTf)3 and furnishes valuable 1,2-diamines in good to excellent yields. Georg Thieme Verlag Stuttgart.
A highly efficient and general method for the ring-opening of aziridines with various nucleophiles in DMSO
Wu, Jie,Sun, Xiaoyu,Sun, Wei
, p. 4231 - 4235 (2008/09/18)
Ring-opening of aziridines with various nucleophiles (such as amines, thiols, and silylated nucleophiles) in DMSO under mild conditions without any catalyst afforded the corresponding products in good to excellent yields. The Royal Society of Chemistry 20
Kinetic resolution of axially chiral 2,2′-dihydroxy-1,1′- biaryls by palladium-catalyzed alcoholysis
Aoyama, Hiroshi,Tokunaga, Makoto,Kiyosu, Junya,Iwasawa, Tetsuo,Obora, Yasushi,Tsuji, Yasushi
, p. 10474 - 10475 (2007/10/03)
Palladium-diamine complexes catalyzed kinetic resolution of axially chiral 2,2′-dihydroxy-1,1′-biaryls by alcoholysis of vinyl ethers. The reaction proceeded with high selectivity for various kinds of biaryls. This process is applicable to not only binaph
