68086-36-2

Upstream product

• 71461-40-0 ethyl (+/-)-cis,trans-3-<(E,Z)-2-chloro-3,3,3-trifluoroprop-1-enyl>-2,2-dimethylcyclopropanecarboxylate 
• 107686-53-3 4-diazoacetoxy-5,5-dichloro-6,6,6-trifluoro-2-methyl-2-hexene 
• 107686-52-2 4-(2,4-dioxobutoxy)-5,5-dichloro-6,6,6-trifluoro-2-methyl-2-hexene 
• 103654-93-9 2,2-dichloro-1,1,1-trifluoro-5-methyl-4-hexen-3-ol 
• 187592-70-7 4-(1,1-dichloro-2,2,2-trifluoroethyl)-6,6-dimethyl-3-oxabicyclo<3.1.0>hexan-2-one 
• 107686-54-4 4-(1,1-Dichloro-2,2,2-trifluoro-ethyl)-6,6-dimethyl-3-oxa-bicyclo[3.1.0]hexan-2-one 

Downstream Products

• 68127-98-0 (+/-)-cis-Z-cyhalothric acid chloride 

Relevant academic research and scientific papers

PRACTICAL AND STEREOCONTROLLED SYNTHESES OF BOTH (1R*,3S*)- AND (1R*,3R*)-3-(2-CHLORO-3,3,3-TRIFLUORO-1-PROPENYL)-2,2-DIMETHYLCYCLOPROPANECARBOXYLATES

The title compounds of (1R*,3S*) configuration were prepared from 3-formyl-2,2-dimethylcyclopropanecarboxylate by addition of CF3CCl2ZnCl, acetylation, and reductive β-elimination with zinc, whereas the (1R*,3R*) isomer was derived from Me2C=CHCH(OH)CCl2CF3 by diazoacetylation, Cu(II) catalyzed intramolecular cyclization, and the zinc reduction.

Synthesis and X-Ray Crystal Structure of a New Potent Pyrethroid Acid, (+/-)-cis-3--2,2-dimethylcyclopropanecarboxylic Acid

Single-crystal X-ray analysis of the title compound has established its structure and molecular geometry.Crystals are monoclinic, space group P21/c, with a = 9.487(4), b = 8.009(4), c = 16.214(6) Angstroem, β = 119.91(1) deg, Z = 4.The structure was solved by direct methods and refined by full-matrix least-squares calculations to R 0.056 over 1242 reflections measured by diffractometer.The crystals contain centrosymmetric hydrogen-bonded dimers (O...O 2.65 Angstroem) in which the carboxy and vinyl substituents are in a 'bisecting' orientation, and the C=O group and one of hydrogen atoms on each methyl group point over the cyclopropane ring.The bond lengths in the ring reflect the substitution pattern.