680971-61-3

Upstream product

• 2524-64-3 chlorophosphoric acid diphenyl ester 
• 680971-62-4 phenyl 2,3-dihydro-4H-1,4-benzoxazin-3-one-4-carboxylate 
• 5466-88-6 3,4-dihydro-3-oxo-2H-1,4-benzoxazine 
• 1885-14-9 phenyl chloroformate 

Downstream Products

• 680971-67-9 3-vinyl-benzo[1,4]oxazine-4-carboxylic acid phenyl ester 
• 797790-41-1 3-benzofuran-2-yl-benzo[1,4]oxazine-4-carboxylic acid phenyl ester 

Relevant academic research and scientific papers

Novel substituted [1,4] benzodioxino[2,3-e] isoindole derivatives, method for preparing and pharmaceutical compositions containing same

Compounds of formula (I): wherein: A is as defined in the description, Y represents a group selected from an oxygen atom and a methylene group, R2 represents a hydrogen atom and in that case: R3 represents a group selected from a hydrogen atom and the groups linear or branched (C1-C6)alkyl, aryl, aryl-(C1-C6)alkyl (in which the alkyl moiety is linear or branched) and SO2CF3, or R2 and R3 form a bond, R1 represents a group selected from a hydrogen atom and the groups linear or branched (C1-C6)alkyl, aryl and aryl-(C1-C6)alkyl (in which the alkyl moiety is linear or branched) or a linear or branched (C1-C6)alkylene chain, Z1 and Z2 each represent a hydrogen atom or Z1 and Z2, together with the carbon atoms carrying them, form a phenyl group. Medicaments.

Easy access to N-aryl, N-heteroarylbenzoxazolinones and 4-aza analogues via Diels-Alder cycloaddition reactions

An improved method for the synthesis of N-aryl, N- heteroarylbenzoxazolinones and their 4-aza analogues is described. The process involves the Diels-Alder cycloaddition of benzoxazinic or pyridoxazinic dienic systems with dienophiles as a key step.