680997-59-5Relevant academic research and scientific papers
Total synthesis of (+)-rishirilide B: Development and application of general processes for enantioselective oxidative dearomatization of resorcinol derivatives
Mejorado, Lupe H.,Pettus, Thomas R. R.
, p. 15625 - 15631 (2007/10/03)
A concise synthesis of (+)-rishirilide B (2) is described. This is the first synthesis to be reported for the (+)-enantiomer of rishirilide B (2) as found in nature. The strategy accentuates the valuable combination of a method for oquinone methide coupli
Diastereoselective dearomatization of resorcinols directed by a lactic acid tether: Unprecedented enantioselective access to p-quinols
Mejorado, Lupe H.,Hoarau, Christophe,Pettus, Thomas R. R.
, p. 1535 - 1538 (2007/10/03)
An operationally simple oxidative dearomatization of resorcinol derivatives is reported that employs an inexpensive chiral directing group. The method provides access to a variety of p-quinol derivatives in good yield and diastereoselectivity. A short red
Cycloadditions of o-quinone dimethides with p-quinol derivatives: Regiocontrolled formation of anthracyclic ring systems
Wang, Junhua,Pettus, Liping H.,Pettus, Thomas R. R.
, p. 1793 - 1796 (2007/10/03)
Regioselective cycloadditions between the cyclohexadienones 12-14 and the ortho-quinone dimethide 19, which is thermally generated from the corresponding 1,3-dihydro-1-methoxy-2,2-dioxide benzo[c]thiophene 27, are reported. The synthetic sequence provides
