681035-75-6Relevant academic research and scientific papers
A stereoselective total synthesis of (+)-α-herbertenol
Srikrishna,Chandrasekhar Babu,Srinivasa Rao
, p. 2125 - 2130 (2007/10/03)
A stereoselective total synthesis of (+)-α-herbertenol starting from the allyl alcohol 12, readily available in three steps from the monoterpene (R)-limonene, is described. Claisen rearrangement of the aryl allyl ether 10 and concomitant cyclisation furnished a 5:3 mixture of the tricyclic compounds 13 and 14. Degradation of the isopropenyl group followed by cleavage of the central ring and functional group manipulation transformed 13 into (+)-α-herbertenol (1b).
