681225-56-9

Upstream product

• 70987-78-9 (S)-Glycidyl tosylate 
• 681225-50-3 (2S)-1-azido-3-chloropropan-2-ol 

Downstream Products

• 936445-12-4 (3S,6R,7R,9aS)-3-(azidomethyl)-6-(3-bromophenyl)-7-methyl-hexahydropyrido[2,1-c][1,4]oxazin-1(6H)-one 
• 936444-98-3 (3S,6R,7R,9aS)-3-(azidomethyl)-6-(4-bromophenyl)-7-methyl-hexahydropyrido[2,1-c][1,4]oxazin-1(6H)-one 
• 936445-25-9 (3S,6S,7S,9aS)-3-(azidomethyl)-6-(3-bromophenyl)-7-methyl-hexahydropyrido[2,1-c][1,4]oxazin-1(6H)-one 
• 936445-15-7 methyl (2S,5S,6S)-1-((S)-3-azido-2-hydroxypropyl)-6-(4-bromophenyl)-5-methylpiperidine-2-carboxylate 
• 936445-17-9 (3S,6S,7S,9aS)-3-(azidomethyl)-6-(4-bromophenyl)-7-methyl-hexahydropyrido[2,1-c][1,4]oxazin-1(6H)-one 
• 1429334-05-3 4-[4-{(R)-2-hydroxy-3-azidopropylamino}phenyl]morpholin-3-one 

Relevant academic research and scientific papers

PROCESS FOR PREPARATION OF OXAZOLIDINONE DERIVATIVES

A process for preparation of oxazolidinone derivatives such as Linezolid and Rivaroxaban using (S)-Epichlorohydrin.

Nucleophilic reaction of glycidol tosylate and the corresponding cyclic sulfate with various nucleophiles: A comparative study

The nucleophilic reaction of glycidol tosylate and the corresponding cyclic sulfate tosylate have been carried out with a number of nucleophiles to study the possible attack of nucleophiles at C1, C2 or C3 positions. The regioselectivity and reactivity of both the substrates i.e. epoxide tosylate 1 and the corresponding cyclic sulfate 2 have been compared and established that under similar conditions cyclic sulfate counterpart shows better regioselectivity and better reactivity than the corresponding epoxide.