681295-00-1Relevant articles and documents
Synthesis of 6-arylvinyl analogues of the HIV drugs SJ-3366 and Emivirine
Wamberg, Michael,Pedersen, Erik B.,El-Brollosy, Nasser R.,Nielsen, Claus
, p. 1141 - 1149 (2004)
This paper reports the synthesis and the antiviral activities of a series of 6-arylvinyl substituted analogues of SJ-3366, a highly potent agent against HIV. The objective was to investigate whether substitution of the 6-arylketone with a 6-arylvinyl grou