681433-87-4Relevant academic research and scientific papers
2-Substituted-16-ene-22-thia-1α,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation, and crystal structure
Shimizu, Masato,Miyamoto, Yukiko,Takaku, Hajime,Matsuo, Mayumi,Nakabayashi, Makoto,Masuno, Hiroyuki,Udagawa, Nobuyuki,DeLuca, Hector F.,Ikura, Teikichi,Ito, Nobutoshi
, p. 6949 - 6964 (2008/12/22)
Recently, we have found that 16-ene-22-thia-26,27-dimethyl-19-norvitamin D3 analogs 1a (n = 2, 3) are 20 times more active than the natural hormone 1α,25-dihydroxyvitamin D3 in terms of transcriptional activity. To further investigat
2,2-DI-SUBSTITUTED 1a,25-DIHYDROXY-19-NORVITAMIN D DERIVATIVE
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Page/Page column 52, (2010/02/13)
An object of the present invention is to provide a novel 2,2-disubstituted-19-norvitamin D derivative. According to the present invention, there is provided a compound represented by the general formula (I): (wherein, R1 and R2 may be the same or differen
