681440-35-7Relevant academic research and scientific papers
New Straightforward Quinoline Synthesis from the Mannich Reaction of α-Ketohydrazones
Bailliez, Vincent,El Kaim, Laurent,Michaut, Valerie
, p. 109 - 118 (2004)
The addition of α-ketohydrazones to 2-acetamidobenzaldehyde proceeds efficiently in the presence of N-benzylpiperazine to afford in good to high yields the expected Mannich adducts; these are easily converted to quinoline derivatives under acidic conditio
