681478-34-2Relevant academic research and scientific papers
Pyrazole-tethered arylphosphine ligands for Suzuki reactions of aryl chlorides: How important is chelation?
Mukherjee, Anuradha,Sarkar, Amitabha
, p. 9525 - 9528 (2004)
Pyrazole-derived bidentate ligands (P,N-donor) with bulky substituents at the 3-position of the pyrazole, 1b-d, were used with Pd2(dba) 3 to carry out efficient Suzuki coupling reactions with both aryl bromides and chlorides. Enhanced catalytic activity on account of steric crowding in the metal complex suggested participation of a chelated structure in the intermediate catalytic steps.
