68175-12-2

Usage

Uses

Used in Pharmaceutical Industry:
6-Bromo-2-ethyl-3H-imidazo[4,5-b]pyridine is utilized as a building block in the synthesis of various biologically active compounds, including potential drug candidates. Its presence in the structure of these compounds contributes to their therapeutic properties and potential applications in treating various diseases and conditions.
Used in Organic Electronic Devices and Materials:
6-Bromo-2-ethyl-3H-imidazo[4,5-b]pyridine has been studied for its potential applications in organic electronic devices and materials due to its unique electronic properties. The presence of the bromine atom in its structure makes it useful for various synthetic transformations and reactions, which can be harnessed to develop new materials with improved performance in electronic applications.

Upstream product

• 38875-53-5 5-bromo-pyridine-2,3-diamine 
• 802294-64-0 propionic acid 
• 78-93-3 butanone 

Relevant academic research and scientific papers

HETEROCYCLIC KINASE INHIBITORS AND PRODUCTS AND USES THEREOF

Compounds are provided having the structure of Formula (I) or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, tautomer, isotope, or salt thereof, wherein A, X, R3, R5, R6, R7, R8, Y

Design, synthesis, biological evaluation and cellular imaging of imidazo[4,5-b]pyridine derivatives as potent and selective TAM inhibitors

The TAM kinase family arises as a new effective and attractive therapeutic target for cancer therapy, autoimmune and viral diseases. A series of 2,6-disubstituted imidazo[4,5-b]pyridines were designed, synthesized and identified as highly potent TAM inhib

QUINAZOLINE DERIVATIVES

Compounds of the formula I in which R, X, L2 and A1-A6 have the meanings indicated in Claim 1, are PI3K inhibitors and can be employed, inter alia, for the treatment of autoimmune diseases, inflammation, cardiovascular diseases, neurodegenerative diseases and tumours.

Heterocyclisation via Selective Elimination: Reaction of 2,3-Diaminopyridine with Acyclic Ketones under Thermal Conditions

Reactions of 2,3-diaminopyridine and its 5-bromo analogue with three symmetrical and nine unsymmetrical acyclic ketones under thermal conditions have been studied.The reactions have yielded 2-substituted-1H-imidazopyridines by the elimination of one of the C2-substituents from the probable, though unisolated, intermediates 2,2-disubstituted-2,3-dihydro-1H-imidazopyridine derivatives.Elimination of one of the groups in the case of symmetrical ketones and preferentially of benzyl group in the case of benzyl methyl ketone has been observed.All the three alkyl phenyl ketones studied afford 2-phenylimidazopyridine by the selective loss of the alkyl group.Elimination of branched alkyl group has been noticed in the reactions involving methyl t-butyl and methyl i-propyl ketones, while the preferential elimination of methyl group is observed in the case of methyl n-alkyl ketones.Suitable explanations have been offered for the observed selective eliminations.