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6-chloro-9-tetradecyl-9H-purine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

68180-22-3

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68180-22-3 Usage

Class

Purines

Composition

Contains a chloro group and a tetradecyl group attached to the purine core

Biological Significance

Found in DNA, RNA, and ATP

Usage

Research tool in biochemistry and pharmacology

Potential Therapeutic Uses

Modulation of signaling pathways

Current Status

Under investigation for potential medical applications

Need for Further Research

Required to fully understand biological activity and medical applications

Check Digit Verification of cas no

The CAS Registry Mumber 68180-22-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,1,8 and 0 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 68180-22:
(7*6)+(6*8)+(5*1)+(4*8)+(3*0)+(2*2)+(1*2)=133
133 % 10 = 3
So 68180-22-3 is a valid CAS Registry Number.

68180-22-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-chloro-9-tetradecylpurine

1.2 Other means of identification

Product number -
Other names 6-Chlor-9-n-tetradecylpurin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:68180-22-3 SDS

68180-22-3Downstream Products

68180-22-3Relevant academic research and scientific papers

Synthesis and anticonvulsant activity of novel purine derivatives

Wang, Shi-Ben,Jin, Peng,Li, Fu-Nan,Quan, Zhe-Shan

, p. 574 - 583 (2015/03/14)

A series of new purines containing triazole and other heterocycle substituents was synthesized and evaluated for their preliminary anticonvulsant activity and neurotoxicity by using the maximal electroshock (MES), subcutaneous pentylenetetrazole (scPTZ) and rotarod neurotoxicity (TOX) tests. Among the compounds studied, 9-decyl-6-(1H-1,2,4-triazol-1-yl)-9H-purine (5e) was the most potent compound, with a median effective dose of 23.4 mg/kg and a high protective index of more than 25.6 after intraperitoneal administration in mice. Compound 5e showed significant oral activity against MESinduced seizures in mice, with an ED50 of 39.4 mg/kg and a PI above 31.6. These results demonstrate that compound 5e possesses better anticonvulsant activity and is safer than the commercially available drugs carbamazepine and valproate in MES, scPTZ and TOX models.

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