681811-55-2Relevant academic research and scientific papers
Synthesis of D- and L-apio nucleoside analogues with 2′-hydroxyl group as potential anti-HIV agents
Jin, Dong Zhe,Kwon, Sung Hee,Moon, Hyung Ryong,Gunaga, Prashantha,Kim, Hea Ok,Kim, Dae-Kee,Chun, Moon Woo,Jeong, Lak Shin
, p. 1101 - 1109 (2007/10/03)
The present work describes the asymmetric synthesis of D- and L-apio-2′,3′-dideoxynucleoside analogues, 4 and 5 with 2′-hydroxyl group via a common intermediate 9, starting from D-galactose. Stereoselective dihydroxylation and deoxygenation through radica
