681836-70-4Relevant articles and documents
RXR-LXR heterodimer modulators for the potential treatment of dyslipidemia
Lagu, Bharat,Pio, Barbara,Lebedev, Rimma,Yang, Maria,Pelton, Patricia D.
, p. 3497 - 3503 (2007)
A number of RXR agonists were synthesized and screened in functional assays. The synthesis and the structure-activity relationship (SAR) within the series of compounds will be presented. Some in vivo data in rodent models for dyslipidemia and diabetes wil
Heterocyclic amide derivatives as RXR agonists for the treatment of dyslipidemia, hypercholesterolemia and diabetes
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Page/Page column 29, (2010/11/26)
The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating RXR mediated disorders. More particularly, the compounds of the present invention are RXR agonists useful for treating RXR mediated disorders.
BENZIMIDAZOLONE COMPOUNDS HAVING 5-HT4 RECEPTOR AGONISTIC ACTIVITY
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Page/Page column 65, (2010/02/11)
This invention provides a compound of the formula (I) or a pharmaceutically acceptable salt thereof, and compositions containing such compounds and the use of such compounds for the manufacture of medicament for gastroesophageal reflux disease, gastrointe
2,4,6-Triaminopyrimidines for the treatment of depression and/or anxiety
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Page/Page column 13, (2010/02/06)
This invention is directed to pyrimidine derivatives which are selective antagonists for the GalR3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceuti