68218-51-9Relevant academic research and scientific papers
FACILE SYNTHESIS OF N-SUBSTITUTED 1H-AZEPINE DERIVATIVES
Ayyangar, Nagaraj R.,Bambal, Ramesh B.,Lugade, Ananda G.
, p. 77 - 82 (2007/10/02)
The facile synthesis of N-sulphonyl and N-ethoxycarbonyl substituted 1H-azepines in high yields by the pressure-induced sulphonylnitrene insertion reaction or, in anhydrous solvents, the 1,3-dipolar azide addition reaction with aromatic substrates containing electron-withdrawing substituents (e.g. dimethyl terephthalate) are described.The probable sequences of reactions involved in the two cases have been indicated.
Antiinflammatory 5,6-Dihydro-11-oxodibenzazepine-3-acetic Acids
Dunn, James P.,Muchowski, Joseph M.,Nelson, Peter N.
, p. 1097 - 1099 (2007/10/02)
A number of 5,6-dihydro-11-oxodibenzazepine-3-acetic acids were synthesized.The compounds were up to ca. 30 times more potent than phenylbutazone as antiinflammatory agents.However, unlike some closely related compounds, for example, the isomeric 2-a
